Youngest of five children born to the peasant family of Egidio Pignalberi and Catherine Proietti. Confirmed on 29 September 1893. Joined the Franciscan Friars Minor Conventual on 30 October 1908 at Zagarolo, Rome, Italy. Studied at the Gregorian University from 1911 to 1913 and the Pontifical Faculty of Saint Bonaventura from 1914 to 1917. He was a friend and classmate of Saint Maximilian Kolbe, and was one of the founders of the Militia of Mary Immaculate. Ordained on 10 August 1917. Worked as a medic on the front lines in World War I. Rector of young seminarians in Rome in 1920. Master of novices first in Bagnoregio, Italy and then to the convent of San Lorenzo in Piglio, Frosinone, Italy where he served for almost 50 years, helping to form the religious lives of generations of Franciscan brothers. Sought after preacher and confessor who travelled throughout the region at the request of bishops and parish priests. After World War II he worked for the reconstruction of communities and recovery of assets damaged and lost in the war. He had a lifelong hobby of repairing clocks, and enjoyed working with precision instruments and technology. Pilgrim to Lourdes, France in 1958. Travelled to Poland in 1971 in connection with the beatification of Saint Maximilian Kolbe. His later years included a series of health issues and eventual confinement to a wheelchair, but he worked with his novice brothers as long as he could.
- 18 July 1982 in Anzio Colonia, Rome, Italy of natural causes
- buried in the family tomb in Serrone, Frosinone, Italy
- re-interred in the chapel of the San Lorenzo monastery in Piglio, Italy on 30 March 1985
- “Venerable Quirico Pignalberi“. CatholicSaints.Info. 25 November 2016. Web. 5 December 2016. <>