Saint Chrysogonus was a Greek, but spent his life in Rome. There is some evidence that he was the instructor of Saint Anastasia, and befriended her when persecution struck her. During the reign of Diocletian he was imprisoned for two years, and then beheaded. His body was cast into the sea, but was afterwards recovered and buried at Zara in Dalmatia, where his relics are still venerated.
A portion of his head is preserved in the church of Chrysogonus in Rome. He is held in great veneration by the Romans and by the Greeks, who call him “the great martyr.”