The eldest of ten children born to Angelo and Maria Romano Clerici; hers was a poor but pious family with two of her brothers becoming monks, one sister a Sister of the Precious Blood. Received a Master’s degree from the College of the Sisters of the Precious Blood in Monza, Italy. Taught in Lainate, Italy from 1880 to 1883. During her time in college and her work as a teacher, Alfonsa had felt a call to religious life, but her work helped support her family, and she stayed with it. She finally answered the call, and on 15 August 1883 joined the Sisters of the Most Precious Blood in Monza. Teacher at the College in Monza. Director of the College on 22 November 1898.
- 13:30 on 14 January 1930 in Vercelli, Italy of a cerebral haemorrhage suffered on the night of 12 to 13 January 1930 while at prayer
- buried in Vercelli
- in 1965 she was re-interred in the cemetery chapel of the College of the Sisters of the Precious Blood in Monza, Italy
- on 1 July 2010 Pope Benedict XVI approved the promulugation of a decree approving a miracle attributed to the intercession of Blessed Alfonsi
- the miracle involved the healing of a nearly-fatal heart condition of Mr Nedo Frosini following the prayers of his wife, Carla Demi Frosini, for the intervention of Blessed Alfonsa
- beatification recognition scheduled for Saturday 23 October 2010, to be held in the Piazza of San Eusebio, Diocese of Vercelli, Italy with Archbishop Angelo Amato as chief celebrant
- “Blessed Alfonsa Clerici“. CatholicSaints.Info. 7 April 2015. Web. 1 December 2015. <>